September 1997 -
April 1998
Prospective validation study of the Los Angeles Prehospital Stroke Screen (LAPSS) performed, demonstrating that LAPSS enables paramedics to accurately identify stroke Subjects in the field.
October 1999   FAST-MAG Pilot Trial grant proposal submitted to NIH-NINDS.
May 2000 -
April 2002
  Pilot Trial performed by three Los Angeles Fire Department ambulances, enrolling 20 subjects and demonstrating feasibility of prehospital administration of magnesium sulfate in focal stroke
October 2001   FAST-MAG Phase 3 Trial grant proposal submitted to NIH-NINDS.
January 2002   Reverse site visit for the FAST-MAG Trial grant in Chicago.
October 2002   FAST-MAG Phase 3 Trial proposal considered by NIH-NINDS Special Emphasis Panel and given high priority score, making funding likely.
February 2003   NIH-NINDS approves funding of FAST-MAG Phase 3 Trial.
September 2003   Notice of Grant award received
October 2003   First bimonthly meeting of the FAST-MAG Trial Steering Committee. Over 20 members attend, representing LA Fire Chiefs, EMS Medical Directors, EMS Provider Agencies, Paramedics, EMS Agency Prehospital Care and Education Coordinators, LA Hospitals Association, ED Nursing, Site Neurology Physicians, and Site ED Physicians.
January 2004   FAST-MAG Investigators Meeting #1 held at Beverly Hills Hotel. Over 20 site investigators attend and help plan study launch.
January 2005   First FAST-MAG Subject Enrolled
February 2005   FAST-MAG Investigators Meeting #2 held at McCormick & Schmick's Restaurant in Pasadena, CA
February 2006   FAST-MAG Investigators Meeting #3 held at McCormick & Schmick's Restaurant in Los Angeles, CA.
March 2006   Subject #100 Enrolled
January 2007   Subject #250 Enrolled
February 2007   FAST-MAG Investigators Meeting #4 held at McCormick & Schmick's Restaurant in El Segundo, CA
April 2007   Subject #325 enrolled - 25% of enrollment goal reached
October 2007   FAST-MAG begins grant renewal process and receives a remarkable priority rating from the NIH Scientific Review Group, placing it in the top 0.1% of all studies requesting renewal.
March 2008   FAST-MAG Investigators Meeting #5 held at McCormick & Schmick's Restaurant in Burbank, CA
March 2008   Subject #500 enrolled
June 2008   Notice of grant renewal award received
October 2008   Subject #649 enrolled - 50% of enrollment goal reached
March 2009   FAST-MAG Investigators Meeting #6 held at McCormick & Schmick's Restaurant in Los Angeles, CA
     
     
 

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